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The University of Houston Mass Spectrometry Laboratory provides fast and high-quality analytical services. We serve researchers at UH, the Texas Medical Center, and other academic institutions as well as the private sector. The laboratory team provides full support that includes consultation, project design, methodology development, and data analysis. 

 

Our facility acquired the Bruker's second generation trapped ion mobility mass spectrometer system (timsTOF Pro) in 2017, which was upgraded to timsTOF Pro 2 in 2022. The timsTOF Pro 2 offers high speed, high sensitivity, and a near 100% duty cycle, thus especially suited for peptide and proteomic analysis of complex biological samples using very low sample amounts (10-200 ng peptides per injection). We offer this instrument exclusively for bottom-up proteomics using both data-dependent and data-independent acquisitions. A wide range of samples have been analyzed in our facility, including cell lysates, tissues, and various body fluids (blood serum, urine, cerebrospinal fluid, tear film, etc.). We have also performed clinical proteomic studies and data analysis. For service fees, please go to the Services & Rates page. 

To request service:​​

We provide full service that includes consultation, project design, methodology development, and data analysis. For a list of our services and fees, please visit our Services & Rates page. 

Announcements

August 2024

Successful installation of Agilent Bravo AssayMap sample preparation automation system and the EvoSep One LC system.

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May 2024

Congratulations on the publication of "A Highly Efficient Click Linker for Enrichment of Alkyne-Tagged Proteins in Living Cells". https://onlinelibrary.wiley.com/doi/10.1002/hlca.202400031

November 2023

Congratulations on the publication of "Intralumenal docking of connexin 36 channels in the ER isolates mistrafficked protein". https://www.sciencedirect.com/science/article/pii/S0021925823023104

February 2023

We are accepting samples.

January 2023

Congratulations on the publication of "Expression and Characterization of Intein-Cyclized Trimer of Staphylococcus aureus Protein A Domain Z". https://www.mdpi.com/2059264

November 2022

Congratulations on the publication of "Subcellular redox responses reveal different Cu-dependent antioxidant defenses between mitochondria and cytosol". https://doi.org/10.1093/mtomcs/mfac087

October 2022

Congratulations on the publication of "Tear proteomic analysis of young glasses, orthokeratology, and soft contact lens wearers". https://doi.org/10.1016/j.jprot.2022.104738

August 2022

timsTOF Pro is upgraded to timsTOF Pro 2.

March 2022

Congratulations on the publication of "Comprehensive spectral libraries for various rabbit eye tissue proteomes".  https://doi.org/10.1038/s41597-022-01241-5

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